Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL39599.1Von Willebrand factor, type A. (393 aa)    
Predicted Functional Partners:
EFL39600.1
ATPase family associated with various cellular activities (AAA).
 
  
 0.840
EFL43224.1
ATPase AAA_5.
 
  
 0.840
EFL37934.1
ATPase family associated with various cellular activities (AAA).
 
  
 0.839
EFL40331.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit.
     
  0.690
EFL43279.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit.
     
  0.690
sucC-2
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.594
EFL39915.1
RtcB.
 
     0.475
EFL38817.1
Conserved hypothetical protein.
  
     0.412
EFL39217.1
Metal-dependent phosphohydrolase, HD region.
     
  0.401
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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