guaB protein (Streptomyces griseoflavus) - STRING interaction network

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guaB

Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (502 aa)

Predicted Functional Partners:

EFL39616.1

0.999

EFL39617.1

0.999

purH

0.994

purA

0.986

EFL39631.1

0.975

EFL41895.1

0.963

rpsB

0.949

ribBA

0.946

EFL40007.1

0.937

EFL42467.1

0.937

Your Current Organism:

Streptomyces griseoflavus

NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL39616.1	EFL39617.1	SSRG_02420	SSRG_02421	GMP synthase.	GMP synthase domain-containing protein.	0.997
EFL39616.1	EFL39631.1	SSRG_02420	SSRG_02435	GMP synthase.	IMP dehydrogenase.	0.992
EFL39616.1	EFL40007.1	SSRG_02420	SSRG_02811	GMP synthase.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.919
EFL39616.1	EFL41895.1	SSRG_02420	SSRG_04699	GMP synthase.	Glutamate synthase large subunit.	0.980
EFL39616.1	EFL42467.1	SSRG_02420	SSRG_05271	GMP synthase.	IMP dehydrogenase.	0.995
EFL39616.1	guaB	SSRG_02420	SSRG_02436	GMP synthase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
EFL39616.1	purA	SSRG_02420	SSRG_02988	GMP synthase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.951
EFL39616.1	purH	SSRG_02420	SSRG_02398	GMP synthase.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.941
EFL39616.1	ribBA	SSRG_02420	SSRG_05284	GMP synthase.	3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.744
EFL39616.1	rpsB	SSRG_02420	SSRG_01643	GMP synthase.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.767
EFL39617.1	EFL39616.1	SSRG_02421	SSRG_02420	GMP synthase domain-containing protein.	GMP synthase.	0.997
EFL39617.1	EFL39631.1	SSRG_02421	SSRG_02435	GMP synthase domain-containing protein.	IMP dehydrogenase.	0.995
EFL39617.1	EFL40007.1	SSRG_02421	SSRG_02811	GMP synthase domain-containing protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.919
EFL39617.1	EFL41895.1	SSRG_02421	SSRG_04699	GMP synthase domain-containing protein.	Glutamate synthase large subunit.	0.980
EFL39617.1	EFL42467.1	SSRG_02421	SSRG_05271	GMP synthase domain-containing protein.	IMP dehydrogenase.	0.998
EFL39617.1	guaB	SSRG_02421	SSRG_02436	GMP synthase domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
EFL39617.1	purA	SSRG_02421	SSRG_02988	GMP synthase domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.955
EFL39617.1	purH	SSRG_02421	SSRG_02398	GMP synthase domain-containing protein.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.941
EFL39617.1	ribBA	SSRG_02421	SSRG_05284	GMP synthase domain-containing protein.	3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.744
EFL39617.1	rpsB	SSRG_02421	SSRG_01643	GMP synthase domain-containing protein.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.767

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