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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL39924.1Signal transduction histidine kinase. (347 aa)    
Predicted Functional Partners:
EFL38760.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
  
 0.995
EFL38759.1
Sensor histidine kinase/response regulator; Overlaps another CDS with the same product name.
   
 0.981
EFL42695.1
Hypothetical protein.
  
 0.959
EFL39925.1
Two-component system response regulator.
 
   0.941
EFL37443.1
PAS/PAC sensor hybrid histidine kinase.
 
0.920
EFL37442.1
PAS/PAC sensor hybrid histidine kinase.
  
 0.915
EFL38729.1
DNA-binding response regulator RegX3.
 
   0.884
EFL39892.1
Two-component system response regulator TcsR4.
  
   0.866
EFL39513.1
DNA-binding response regulator MtrA.
  
   0.865
EFL38352.1
DNA-binding response regulator ResD.
  
   0.864
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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