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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL39944.1RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (257 aa)    
Predicted Functional Partners:
EFL39945.1
Conserved hypothetical protein.
 
 
   0.999
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.754
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.746
EFL39144.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.703
EFL39219.1
TIGR02947 family RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.685
EFL39512.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.670
EFL38123.1
Sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.634
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.628
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.628
EFL43268.1
Sigma-70 region 2 subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.617
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.