STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaANa+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (478 aa)    
Predicted Functional Partners:
acsA
acetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.739
EFL40063.1
Integral membrane transporter.
       0.680
EFL40064.1
Alpha/beta hydrolase fold protein.
       0.626
EFL39467.1
Conserved hypothetical protein.
  
    0.580
EFL38826.1
Integral membrane protein.
   
    0.573
EFL39783.1
Conserved hypothetical protein.
   
    0.573
EFL40623.1
Membrane protein.
   
    0.573
EFL41377.1
Integral membrane protein.
   
    0.573
EFL42146.1
Regulatory protein.
   
    0.573
EFL42859.1
Conserved hypothetical protein.
   
    0.573
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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