Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
EFL40360.1Membrane spanning protein DUF881. (259 aa)    
Predicted Functional Partners:
EFL42526.1
Conserved hypothetical protein.
 
  
 0.904
EFL42527.1
Membrane protein.
  
     0.774
crgA
WhiP protein; Involved in cell division; Belongs to the CrgA family.
       0.770
EFL40357.1
Integral membrane protein.
       0.742
EFL40358.1
Anthranilate synthase component II.
       0.742
EFL40359.1
Membrane protein; Unextendable partial coding region.
       0.742
EFL40356.1
Integral membrane protein.
       0.737
disA
DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.507
EFL40510.1
Conserved hypothetical protein.
  
     0.497
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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