Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL40436.1HAD-superfamily hydrolase, subfamily IIB. (295 aa)    
Predicted Functional Partners:
EFL40561.1
Riboflavin/cytosine deaminase.
    
 0.824
EFL40437.1
Conserved hypothetical protein.
       0.765
EFL42524.1
Phosphoglucomutase/phosphomannomutase.
  
 
 0.701
EFL40438.1
Conserved hypothetical protein.
       0.696
kptA
RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
       0.696
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.668
EFL38775.1
Riboflavin biosynthesis protein RibF.
   
 0.655
EFL37481.1
PTS system, IIBC component.
    
 0.623
EFL40442.1
ABC transporter ATP-binding protein.
   
   0.590
EFL40444.1
ABC transporter, ATP-binding protein.
   
   0.590
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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