Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL40477.1GCN5 N-acetyltransferase. (286 aa)    
Predicted Functional Partners:
EFL40798.1
Acetyltransferase.
 
     0.620
EFL37813.1
Metallo-beta-lactamase.
       0.552
EFL40797.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
       0.552
arc
AAA family ATPase, pupylation-associated; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
    0.516
EFL40642.1
PbsX family transcriptional regulator.
 
     0.515
EFL41980.1
Integral membrane.
  
    0.504
EFL40825.1
Transcriptional regulator.
  
     0.501
EFL40476.1
Integrase; Belongs to the 'phage' integrase family.
       0.435
EFL41605.1
Zinc ribbon domain-containing protein.
       0.433
EFL41606.1
Phosphoglycerate mutase.
       0.433
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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