STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Coexpression
Experiments
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[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)    
Predicted Functional Partners:
EFL39510.1
Uridine kinase.
  
 0.984
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.978
EFL41946.1
Conserved hypothetical protein.
  
 0.951
EFL39879.1
Cytosine deaminase.
   
 0.947
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.937
EFL39527.1
Thymidine phosphorylase.
 
  
 0.927
EFL41353.1
Ribose 5-phosphate isomerase.
 
    0.909
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
 
 0.890
EFL39739.1
Hydrolase; Truncated CDS; unextendable partial coding region.
  
 
 0.881
pyrR
PyrR bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.880
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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