STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL40552.1Valine dehydrogenase (ValDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (362 aa)    
Predicted Functional Partners:
EFL41895.1
Glutamate synthase large subunit.
  
 0.999
EFL38917.1
Branched-chain amino acid aminotransferase.
  
 
 0.908
EFL42390.1
Aminotransferase.
  
 
 0.908
EFL40309.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
  
 
 0.891
EFL39170.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
  
 0.890
EFL43231.1
ferredoxin-NADP reductase.
  
 0.878
EFL43484.1
Polyketide synthase.
    
 0.859
EFL38916.1
2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.825
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
   
 
 0.825
EFL38049.1
NAD-dependent deacetylase 2.
    
 0.822
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.