STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL40632.1Hydrolase. (272 aa)    
Predicted Functional Partners:
EFL40631.1
GntR-family transcriptional regulator.
 
     0.946
EFL41130.1
Oxidoreductase, FAD-binding.
    
 0.893
EFL40634.1
ATP-dependent DNA helicase.
 
     0.807
EFL40851.1
Secreted protein.
  
 
   0.787
EFL42522.1
PTS system, glucose-specific IIABC component.
   
 
  0.777
EFL40633.1
TetR family transcriptional regulator.
 
     0.713
EFL42467.1
IMP dehydrogenase.
    
  0.687
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.675
EFL37481.1
PTS system, IIBC component.
    
  0.659
EFL39708.1
Xre family toxin-antitoxin system, antitoxin component.
  
     0.659
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.