Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL40674.1Guanyltransferase. (243 aa)    
Predicted Functional Partners:
EFL40675.1
Conserved hypothetical protein.
     
 0.872
EFL39505.1
Phosphomannomutase.
  
 
 0.862
EFL41028.1
Phosphomannomutase.
  
 
 0.859
EFL38231.1
HAD-superfamily hydrolase subfamily IIIA; Truncated CDS.
  
 0.829
EFL41382.1
Glucose-1-phosphate thymidylyltransferase.
 
 
0.816
EFL43054.1
Glucose-1-phosphate thymidylyltransferase.
 
 
0.811
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
 
 0.787
EFL39947.1
NAD-dependent epimerase/dehydratase.
  
 0.786
EFL38550.1
GDP-mannose 6-dehydrogenase AlgD; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.780
EFL40863.1
PTS system, fructose-specific family, IIABC component.
     
  0.765
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: medium (62%) [HD]