Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL40863.1PTS system, fructose-specific family, IIABC component. (480 aa)    
Predicted Functional Partners:
EFL40862.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
EFL40689.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.998
EFL42805.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.998
EFL42521.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.996
EFL38677.1
HPr family phosphocarrier.
 
 
 0.993
EFL41031.1
Phosphomannose isomerase type I.
  
 
 0.982
EFL42522.1
PTS system, glucose-specific IIABC component.
  
 
 0.972
EFL37481.1
PTS system, IIBC component.
  
  
 0.963
EFL40202.1
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.934
EFL42806.1
Fructose-1,6-bisphosphate aldolase, class II.
  
 
 0.934
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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