Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL41098.1RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)    
Predicted Functional Partners:
EFL41099.1
Membrane protein.
 
 
 0.996
EFL42935.1
Membrane protein.
 
 
 0.930
EFL41100.1
I DNA or RNA helicase.
       0.829
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.825
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.759
EFL41097.1
Conserved hypothetical protein.
       0.728
EFL39512.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.721
EFL39144.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.708
EFL39552.1
RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.706
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.706
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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