Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL41392.1Integral membrane protein. (628 aa)    
Predicted Functional Partners:
ispD-2
Pyrophosphorylase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.892
EFL41395.1
Conserved hypothetical protein.
 
     0.764
EFL40291.1
Mucin-2.
 
     0.747
EFL39535.1
Conserved hypothetical protein.
  
     0.693
EFL43289.1
Conserved hypothetical protein.
  
     0.676
EFL37834.1
Nucleotide sugar-1-phosphate transferase.
 
  
 0.669
EFL42295.1
Conserved hypothetical protein.
  
     0.669
EFL40680.1
Conserved hypothetical protein.
  
     0.562
EFL40817.1
Integral membrane protein.
 
     0.559
EFL42867.1
SecD/SecF/SecDF export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
     
  0.557
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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