Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL41570.1S-layer domain-containing protein. (214 aa)    
Predicted Functional Partners:
EFL39616.1
GMP synthase.
    
  0.716
EFL39617.1
GMP synthase domain-containing protein.
    
  0.716
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.689
EFL41495.1
Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.
  
     0.657
EFL41569.1
Conserved hypothetical protein.
       0.609
EFL42015.1
Endonuclease/exonuclease/phosphatase.
 
   
 0.606
EFL41854.1
Metalloprotease MEP1-like protein.
  
     0.569
EFL41571.1
Integral membrane protein.
       0.552
EFL41572.1
2-deoxyglucose-6-phosphate phosphatase.
       0.552
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.550
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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