STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (292 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.985
EFL37973.1
2-dehydropantoate 2-reductase.
    
 0.948
EFL38917.1
Branched-chain amino acid aminotransferase.
    
 0.893
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.879
EFL42390.1
Aminotransferase.
    
 0.872
EFL42032.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.866
EFL39990.1
NADP oxidoreductase coenzyme F420-dependent family protein.
 
  
 0.856
EFL41691.1
Transmembrane efflux protein; Belongs to the major facilitator superfamily.
       0.756
EFL41688.1
ABC-transporter, transmembrane component.
       0.750
EFL39988.1
Nicotinate-nucleotide diphosphorylase; Belongs to the NadC/ModD family.
     0.681
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.