| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFL38389.1 | EFL38654.1 | SSRG_01193 | SSRG_01458 | Ribonuclease D. | Conserved hypothetical protein. | 0.575 |
| EFL38389.1 | EFL41732.1 | SSRG_01193 | SSRG_04536 | Ribonuclease D. | Integral membrane protein. | 0.549 |
| EFL38389.1 | EFL42531.1 | SSRG_01193 | SSRG_05335 | Ribonuclease D. | MerR family transcriptional regulator. | 0.522 |
| EFL38389.1 | glnE | SSRG_01193 | SSRG_04507 | Ribonuclease D. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.701 |
| EFL38389.1 | rbpA-2 | SSRG_01193 | SSRG_05302 | Ribonuclease D. | Membrane-associated GTPase; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | 0.542 |
| EFL38654.1 | EFL38389.1 | SSRG_01458 | SSRG_01193 | Conserved hypothetical protein. | Ribonuclease D. | 0.575 |
| EFL38654.1 | EFL41732.1 | SSRG_01458 | SSRG_04536 | Conserved hypothetical protein. | Integral membrane protein. | 0.766 |
| EFL38654.1 | EFL42531.1 | SSRG_01458 | SSRG_05335 | Conserved hypothetical protein. | MerR family transcriptional regulator. | 0.772 |
| EFL38654.1 | glnE | SSRG_01458 | SSRG_04507 | Conserved hypothetical protein. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.685 |
| EFL38654.1 | rbpA-2 | SSRG_01458 | SSRG_05302 | Conserved hypothetical protein. | Membrane-associated GTPase; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | 0.774 |
| EFL38859.1 | EFL41698.1 | SSRG_01663 | SSRG_04502 | Nitrogen regulatory protein P-II. | Glutamine synthetase, type I. | 0.836 |
| EFL38859.1 | EFL41730.1 | SSRG_01663 | SSRG_04534 | Nitrogen regulatory protein P-II. | Glutamine synthetase, type I. | 0.894 |
| EFL38859.1 | EFL41895.1 | SSRG_01663 | SSRG_04699 | Nitrogen regulatory protein P-II. | Glutamate synthase large subunit. | 0.885 |
| EFL38859.1 | glnD | SSRG_01663 | SSRG_01662 | Nitrogen regulatory protein P-II. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.998 |
| EFL38859.1 | glnE | SSRG_01663 | SSRG_04507 | Nitrogen regulatory protein P-II. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.664 |
| EFL41698.1 | EFL38859.1 | SSRG_04502 | SSRG_01663 | Glutamine synthetase, type I. | Nitrogen regulatory protein P-II. | 0.836 |
| EFL41698.1 | EFL41730.1 | SSRG_04502 | SSRG_04534 | Glutamine synthetase, type I. | Glutamine synthetase, type I. | 0.883 |
| EFL41698.1 | EFL41895.1 | SSRG_04502 | SSRG_04699 | Glutamine synthetase, type I. | Glutamate synthase large subunit. | 0.971 |
| EFL41698.1 | EFL42531.1 | SSRG_04502 | SSRG_05335 | Glutamine synthetase, type I. | MerR family transcriptional regulator. | 0.439 |
| EFL41698.1 | glnD | SSRG_04502 | SSRG_01662 | Glutamine synthetase, type I. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.564 |
