Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL41745.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. (601 aa)    
Predicted Functional Partners:
EFL41746.1
Dihydrolipoyl dehydrogenase.
 0.999
EFL37735.1
Pyruvate dehydrogenase complex, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.995
EFL41743.1
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.994
EFL39170.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
0.989
EFL40308.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.989
EFL40309.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
 
 0.989
EFL40321.1
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.987
EFL41553.1
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.986
EFL41278.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.981
EFL40776.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.975
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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