Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL41996.1Amidohydrolase 2. (130 aa)    
Predicted Functional Partners:
EFL41997.1
Nucleotidyltransferase domain-containing protein.
       0.854
EFL40331.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit.
    
  0.683
EFL43279.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit.
    
  0.683
EFL42826.1
Conserved hypothetical protein.
     
 0.623
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
       0.552
EFL41995.1
Conserved hypothetical protein.
       0.552
EFL42828.1
Conserved hypothetical protein.
  
   
 0.499
EFL38816.1
Aldehyde dehydrogenase (NAD) family protein; Belongs to the aldehyde dehydrogenase family.
     
 0.437
EFL38430.1
Conserved hypothetical protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
    
 0.434
EFL39927.1
2-pyrone-4,6-dicarboxylate lactonase.
    
 0.434
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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