Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (442 aa)    
Predicted Functional Partners:
EFL41128.1
4-hydroxyphenylpyruvate dioxygenase.
 
 0.996
EFL39802.1
Fumarylacetoacetase.
 
  
 0.980
EFL37899.1
4-hydroxyphenylpyruvate dioxygenase.
  
 0.916
EFL39053.1
methylmalonyl-CoA epimerase.
  
 0.875
EFL42195.1
GntR-family transcriptional regulator.
       0.840
EFL40768.1
Conserved hypothetical protein.
  
 0.830
EFL42194.1
Conserved hypothetical protein; Unextendable partial coding region.
       0.811
EFL42197.1
Secreted protein.
       0.763
EFL42198.1
TetR-family transcriptional regulator.
       0.763
EFL42911.1
Fumarylacetoacetate hydrolase.
  
  
 0.708
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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