close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL42198.1TetR-family transcriptional regulator. (202 aa)    
Predicted Functional Partners:
EFL42197.1
Secreted protein.
 
     0.891
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
       0.772
EFL42199.1
Oxidoreductase, molybdopterin-binding.
 
    0.756
EFL42195.1
GntR-family transcriptional regulator.
       0.752
EFL42194.1
Conserved hypothetical protein; Unextendable partial coding region.
       0.737
EFL42201.1
Citrate transporter.
       0.685
EFL42200.1
Oxidoreductase, molybdopterin-binding.
 
    0.673
EFL42202.1
Integral membrane transporter; Unextendable partial coding region.
       0.656
EFL42204.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
       0.572
EFL38319.1
Subtilisin inhibitor (SSI type); Belongs to the protease inhibitor I16 (SSI) family.
  
     0.429
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.