Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL42249.1hAD-superfamily hydrolase subfamily IA, variant 3:HAD-superfamily hydrolase, subfamily IA. (233 aa)    
Predicted Functional Partners:
EFL37738.1
Conserved hypothetical protein.
  
    0.803
EFL42248.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.758
EFL39617.1
GMP synthase domain-containing protein.
 
 
  0.746
EFL39616.1
GMP synthase.
 
 
  0.743
EFL42247.1
Glycerol operon regulatory protein; Truncated CDS.
       0.664
EFL42246.1
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
   0.645
EFL42244.1
Glycerol-3-phosphate dehydrogenase.
     
 0.615
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.609
glpK-2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.551
EFL37410.1
Oxidoreductase, FAD-binding.
    
  0.547
Your Current Organism:
Streptomyces griseoflavus
NCBI taxonomy Id: 467200
Other names: S. griseoflavus Tu4000, Streptomyces griseoflavus Tu4000, Streptomyces griseoflavus str. Tu4000, Streptomyces griseoflavus strain Tu4000
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