STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFKEGG: csh:Closa_1598 9.0e-112 orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96; Belongs to the OMP decarboxylase family. Type 2 subfamily. (320 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.999
pyrD
Dihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.996
pyrB
KEGG: csh:Closa_2185 2.2e-133 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.973
KXB53568.1
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: rho:RHOM_10050 9.4e-46 aspartate carbamoyltransferase regulatory subunit K00610; Psort location: Cytoplasmic, score: 8.96.
  
 
  0.958
pyrK
Putative dihydroorotate oxidase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
 
 0.950
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.950
carA
KEGG: csh:Closa_1281 2.5e-141 carbamoyl-phosphate synthase small subunit; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarA family.
  
  
 0.940
carB
KEGG: csh:Closa_1282 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family.
 
  
 0.872
pyrC
Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.853
KXB57282.1
UMP kinase domain protein; KEGG: eel:EUBELI_00848 1.4e-28 uridylate kinase; K09903 uridylate kinase; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.834
Your Current Organism:
Lachnoanaerobaculum saburreum
NCBI taxonomy Id: 467210
Other names: ATCC 33271, CCUG 28089, CIP 105341, Catenabacterium saburreum, DSM 3986, Eubacterium saburreum, JCM 11021, L. saburreum, Leptotrichia aerogenes, VPI 11763
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