node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB55646.1 | mfd | HMPREF1866_02022 | HMPREF1866_00734 | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.561 |
KXB55646.1 | mutL | HMPREF1866_02022 | HMPREF1866_02569 | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.443 |
KXB55646.1 | polA | HMPREF1866_02022 | HMPREF1866_00305 | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.491 |
KXB55646.1 | uvrA | HMPREF1866_02022 | HMPREF1866_00340 | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.991 |
KXB55646.1 | uvrC | HMPREF1866_02022 | HMPREF1866_01815 | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.983 |
KXB60556.1 | KXB60557.1 | HMPREF1866_00337 | HMPREF1866_00338 | KEGG: cpy:Cphy_0577 5.6e-277 hypothetical protein; K15533 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Psort location: Cytoplasmic, score: 8.96. | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | 0.945 |
KXB60556.1 | aroK-2 | HMPREF1866_00337 | HMPREF1866_00339 | KEGG: cpy:Cphy_0577 5.6e-277 hypothetical protein; K15533 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Psort location: Cytoplasmic, score: 8.96. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.737 |
KXB60556.1 | uvrA | HMPREF1866_00337 | HMPREF1866_00340 | KEGG: cpy:Cphy_0577 5.6e-277 hypothetical protein; K15533 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Psort location: Cytoplasmic, score: 8.96. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.590 |
KXB60557.1 | KXB60556.1 | HMPREF1866_00338 | HMPREF1866_00337 | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_0577 5.6e-277 hypothetical protein; K15533 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Psort location: Cytoplasmic, score: 8.96. | 0.945 |
KXB60557.1 | aroK-2 | HMPREF1866_00338 | HMPREF1866_00339 | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.737 |
KXB60557.1 | polA | HMPREF1866_00338 | HMPREF1866_00305 | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.444 |
KXB60557.1 | uvrA | HMPREF1866_00338 | HMPREF1866_00340 | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.590 |
aroK-2 | KXB60556.1 | HMPREF1866_00339 | HMPREF1866_00337 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | KEGG: cpy:Cphy_0577 5.6e-277 hypothetical protein; K15533 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Psort location: Cytoplasmic, score: 8.96. | 0.737 |
aroK-2 | KXB60557.1 | HMPREF1866_00339 | HMPREF1866_00338 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Putative mucin-desulfating sulfatase; KEGG: bbi:BBIF_0997 1.7e-78 Mucin desulfatase; K13059 N-acetylhexosamine 1-kinase; Psort location: Cytoplasmic, score: 8.96. | 0.737 |
aroK-2 | uvrA | HMPREF1866_00339 | HMPREF1866_00340 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.664 |
dnaJ | mutL | HMPREF1866_00877 | HMPREF1866_02569 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.416 |
dnaJ | polA | HMPREF1866_00877 | HMPREF1866_00305 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.555 |
dnaJ | uvrA | HMPREF1866_00877 | HMPREF1866_00340 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.579 |
mfd | KXB55646.1 | HMPREF1866_00734 | HMPREF1866_02022 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Hypothetical protein; KEGG: gfo:GFO_2292 4.4e-10 uvrB; excinuclease ABC subunit B K03702; Psort location: Cytoplasmic, score: 9.26. | 0.561 |
mfd | mutL | HMPREF1866_00734 | HMPREF1866_02569 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.531 |