STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB60162.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (384 aa)    
Predicted Functional Partners:
KXB60161.1
Hypothetical protein.
       0.746
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.720
KXB60160.1
Hypothetical protein.
       0.689
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
   0.658
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.537
KXB53957.1
Pyruvate kinase; KEGG: csh:Closa_0670 8.7e-162 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
    
   0.537
KXB60158.1
Hypothetical protein; KEGG: mpe:MYPE6470 1.7e-05 DNA topoisomerase IV subunit A; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 8.96.
       0.530
KXB60159.1
Hypothetical protein; KEGG: mcc:715086 0.00012 SLK; STE20-like kinase; K08836 STE20-like kinase; Psort location: Cytoplasmic, score: 8.96.
       0.530
KXB55741.1
Hypothetical protein; KEGG: ctc:CTC01788 4.5e-05 RNA polymerase factor sigma-70 K03088; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.509
KXB60157.1
Hypothetical protein; KEGG: tpd:Teth39_1928 0.0038 glycoside hydrolase family protein; K01192 beta-mannosidase; Psort location: Cytoplasmic, score: 8.96.
       0.488
Your Current Organism:
Lachnoanaerobaculum saburreum
NCBI taxonomy Id: 467210
Other names: ATCC 33271, CCUG 28089, CIP 105341, Catenabacterium saburreum, DSM 3986, Eubacterium saburreum, JCM 11021, L. saburreum, Leptotrichia aerogenes, VPI 11763
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