| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB56796.1 | KXB59229.1 | HMPREF1866_01706 | HMPREF1866_01045 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | 0.990 |
| KXB56796.1 | KXB59230.1 | HMPREF1866_01706 | HMPREF1866_01046 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.924 |
| KXB56796.1 | KXB59231.1 | HMPREF1866_01706 | HMPREF1866_01047 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | Cobalt chelatase; KEGG: cpy:Cphy_1387 7.2e-48 anaerobic cobalt chelatase; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 8.96. | 0.984 |
| KXB56796.1 | KXB59232.1 | HMPREF1866_01706 | HMPREF1866_01048 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | Porphobilinogen synthase; KEGG: cpy:Cphy_1372 1.2e-111 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 9.97; Belongs to the ALAD family. | 0.685 |
| KXB56796.1 | KXB59233.1 | HMPREF1866_01706 | HMPREF1866_01049 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpy:Cphy_1369 1.3e-25 siroheme synthase; K02304 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Psort location: Cytoplasmic, score: 9.97. | 0.983 |
| KXB56796.1 | hemA | HMPREF1866_01706 | HMPREF1866_01043 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.730 |
| KXB56796.1 | hemL | HMPREF1866_01706 | HMPREF1866_01044 | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: rho:RHOM_04605 1.4e-136 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.97. | 0.683 |
| KXB56818.1 | guaA | HMPREF1866_01728 | HMPREF1866_00420 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.422 |
| KXB56818.1 | hemL | HMPREF1866_01728 | HMPREF1866_01044 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: rho:RHOM_04605 1.4e-136 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.97. | 0.602 |
| KXB57193.1 | hemL | HMPREF1866_01588 | HMPREF1866_01044 | [acyl-carrier-protein] S-malonyltransferase; KEGG: cpy:Cphy_0516 1.9e-72 malonyl CoA-acyl carrier protein transacylase; K00645 [acyl-carrier-protein] S-malonyltransferase; Psort location: Cytoplasmic, score: 9.97. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: rho:RHOM_04605 1.4e-136 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.97. | 0.900 |
| KXB59229.1 | KXB56796.1 | HMPREF1866_01045 | HMPREF1866_01706 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | 0.990 |
| KXB59229.1 | KXB59230.1 | HMPREF1866_01045 | HMPREF1866_01046 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| KXB59229.1 | KXB59231.1 | HMPREF1866_01045 | HMPREF1866_01047 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | Cobalt chelatase; KEGG: cpy:Cphy_1387 7.2e-48 anaerobic cobalt chelatase; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 8.96. | 0.979 |
| KXB59229.1 | KXB59232.1 | HMPREF1866_01045 | HMPREF1866_01048 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | Porphobilinogen synthase; KEGG: cpy:Cphy_1372 1.2e-111 delta-aminolevulinic acid dehydratase K01698; Psort location: Cytoplasmic, score: 9.97; Belongs to the ALAD family. | 0.999 |
| KXB59229.1 | KXB59233.1 | HMPREF1866_01045 | HMPREF1866_01049 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | KEGG: cpy:Cphy_1369 1.3e-25 siroheme synthase; K02304 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| KXB59229.1 | hemA | HMPREF1866_01045 | HMPREF1866_01043 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.991 |
| KXB59229.1 | hemL | HMPREF1866_01045 | HMPREF1866_01044 | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: rho:RHOM_04605 1.4e-136 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.97. | 0.996 |
| KXB59230.1 | KXB56796.1 | HMPREF1866_01046 | HMPREF1866_01706 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | precorrin-6A reductase; KEGG: cpy:Cphy_1379 1.7e-48 precorrin-6x reductase; K00595 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase; Psort location: Cytoplasmic, score: 8.96. | 0.924 |
| KXB59230.1 | KXB59229.1 | HMPREF1866_01046 | HMPREF1866_01045 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | uroporphyrinogen-III C-methyltransferase; KEGG: cdf:CD3420 5.6e-96 hemD; porphyrin biosynthesis protein K13542; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| KXB59230.1 | KXB59231.1 | HMPREF1866_01046 | HMPREF1866_01047 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Cobalt chelatase; KEGG: cpy:Cphy_1387 7.2e-48 anaerobic cobalt chelatase; K02190 sirohydrochlorin cobaltochelatase; Psort location: Cytoplasmic, score: 8.96. | 0.889 |