STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)    
Predicted Functional Partners:
KXB57492.1
Putative phosphoglycerate dehydrogenase; KEGG: csh:Closa_3653 6.0e-138 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 0.999
KXB60042.1
Cysteine synthase A; KEGG: eel:EUBELI_00752 8.0e-120 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.923
KXB53526.1
Threonine synthase; KEGG: csh:Closa_0463 1.1e-175 threonine synthase K01733; Psort location: Cytoplasmic, score: 9.97.
   
 0.923
KXB60757.1
Chorismate mutase; KEGG: cno:NT01CX_0622 2.3e-19 chorismate mutase; K04093 chorismate mutase.
  
  
 0.879
KXB53574.1
Prephenate dehydratase; KEGG: bpb:bpr_I1730 1.8e-74 pheA; chorismate mutase K14170; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.879
KXB57827.1
KEGG: csh:Closa_3618 3.5e-133 4-hydroxythreonine-4-phosphate dehydrogenase K00097; Psort location: Cytoplasmic, score: 9.97; Belongs to the PdxA family.
     
 0.856
ilvD
KEGG: csh:Closa_3656 3.7e-234 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
  
 
 0.798
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.736
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
      0.734
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.703
Your Current Organism:
Lachnoanaerobaculum saburreum
NCBI taxonomy Id: 467210
Other names: ATCC 33271, CCUG 28089, CIP 105341, Catenabacterium saburreum, DSM 3986, Eubacterium saburreum, JCM 11021, L. saburreum, Leptotrichia aerogenes, VPI 11763
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