STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa)    
Predicted Functional Partners:
KXB54890.1
Adenylosuccinate lyase; KEGG: csh:Closa_1579 5.3e-194 adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.991
KXB56828.1
AICARFT/IMPCHase bienzyme; KEGG: rho:RHOM_09910 6.5e-157 5-aminoimidazole-4-carboxamide ribonucleotide transformylase K00602; Psort location: Cytoplasmic, score: 9.97.
  
 0.981
KXB59985.1
KEGG: csh:Closa_1348 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.94.
  
  
 0.977
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.950
purC
KEGG: csh:Closa_1577 4.6e-101 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 9.97; Belongs to the SAICAR synthetase family.
  
 0.942
KXB59211.1
KEGG: csh:Closa_4061 2.0e-59 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.924
argG
KEGG: csh:Closa_3289 4.6e-195 argininosuccinate synthase K01940; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.919
pyrB
KEGG: csh:Closa_2185 2.2e-133 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.914
KXB59986.1
Aspartate kinase; KEGG: csh:Closa_0940 3.5e-181 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family.
  
 
  0.901
Your Current Organism:
Lachnoanaerobaculum saburreum
NCBI taxonomy Id: 467210
Other names: ATCC 33271, CCUG 28089, CIP 105341, Catenabacterium saburreum, DSM 3986, Eubacterium saburreum, JCM 11021, L. saburreum, Leptotrichia aerogenes, VPI 11763
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