STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribBA3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (405 aa)    
Predicted Functional Partners:
KXB52882.1
KEGG: rho:RHOM_16840 1.8e-161 riboflavin biosynthesis protein RibD; K11752 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase; Psort location: Cytoplasmic, score: 9.97.
 0.999
KXB52883.1
KEGG: rho:RHOM_16835 6.5e-86 riboflavin synthase subunit alpha; K00793 riboflavin synthase; Psort location: Cytoplasmic, score: 9.97.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
KXB55039.1
Kinase domain protein; KEGG: ova:OBV_34190 2.7e-71 hypothetical protein; K08884 serine/threonine protein kinase, bacterial; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.947
KXB54868.1
Kinase domain protein; KEGG: ova:OBV_34190 1.7e-28 hypothetical protein; K08884 serine/threonine protein kinase, bacterial.
  
 
 0.947
KXB57474.1
PPR repeat protein; KEGG: kol:Kole_1440 1.1e-11 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.944
tadA
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.926
KXB60398.1
KEGG: csh:Closa_2978 3.0e-65 riboflavin biosynthesis protein RibF; K11753 riboflavin kinase / FMN adenylyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.924
KXB55598.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bpb:bpr_I0037 1.8e-74 two component system histidine kinase; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
  0.919
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.912
Your Current Organism:
Lachnoanaerobaculum saburreum
NCBI taxonomy Id: 467210
Other names: ATCC 33271, CCUG 28089, CIP 105341, Catenabacterium saburreum, DSM 3986, Eubacterium saburreum, JCM 11021, L. saburreum, Leptotrichia aerogenes, VPI 11763
Server load: low (28%) [HD]