node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
pdam_00006233 | pdam_00007824 | A0A3M6URC1 | A0A3M6TXT6 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.858 |
pdam_00006233 | pdam_00008484 | A0A3M6URC1 | A0A3M6U4I5 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.948 |
pdam_00006233 | pdam_00009838 | A0A3M6URC1 | A0A3M6TLV4 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | SHMT domain-containing protein. | 0.902 |
pdam_00006233 | pdam_00010320 | A0A3M6URC1 | A0A3M6UDF0 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.990 |
pdam_00006233 | pdam_00011251 | A0A3M6URC1 | A0A3M6U6P0 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Phosphoserine aminotransferase. | 0.705 |
pdam_00006233 | pdam_00014841 | A0A3M6URC1 | A0A3M6UCY9 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 2-Hacid_dh_C domain-containing protein. | 0.738 |
pdam_00006233 | pdam_00015858 | A0A3M6URC1 | A0A3M6TKA9 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | PRA-CH domain-containing protein. | 0.786 |
pdam_00006233 | pdam_00016763 | A0A3M6URC1 | A0A3M6TBW5 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.589 |
pdam_00006233 | pdam_00019257 | A0A3M6URC1 | A0A3M6URN5 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Uncharacterized protein. | 0.984 |
pdam_00006233 | pdam_00019571 | A0A3M6URC1 | A0A3M6UG94 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.860 |
pdam_00007824 | pdam_00006233 | A0A3M6TXT6 | A0A3M6URC1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.858 |
pdam_00007824 | pdam_00008484 | A0A3M6TXT6 | A0A3M6U4I5 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.677 |
pdam_00007824 | pdam_00009838 | A0A3M6TXT6 | A0A3M6TLV4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | SHMT domain-containing protein. | 0.858 |
pdam_00007824 | pdam_00010320 | A0A3M6TXT6 | A0A3M6UDF0 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.574 |
pdam_00007824 | pdam_00014841 | A0A3M6TXT6 | A0A3M6UCY9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 2-Hacid_dh_C domain-containing protein. | 0.808 |
pdam_00007824 | pdam_00019257 | A0A3M6TXT6 | A0A3M6URN5 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.579 |
pdam_00007824 | pdam_00019571 | A0A3M6TXT6 | A0A3M6UG94 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.825 |
pdam_00008484 | pdam_00006233 | A0A3M6U4I5 | A0A3M6URC1 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.948 |
pdam_00008484 | pdam_00007824 | A0A3M6U4I5 | A0A3M6TXT6 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.677 |
pdam_00008484 | pdam_00009838 | A0A3M6U4I5 | A0A3M6TLV4 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | SHMT domain-containing protein. | 0.947 |