STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEE38622.1Sensor histidine kinase; [T] COG0642 Signal transduction histidine kinase. (460 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.988
EEE39145.1
Sensor histidine kinase/response regulator; [T] COG0642 Signal transduction histidine kinase.
 
 0.972
EEE35206.1
Sensory box histidine kinase/response regulator; [T] COG0642 Signal transduction histidine kinase.
 
 
 0.971
EEE36915.1
Two component transcriptional regulator, winged helix family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.901
EEE36494.1
Response regulator receiver modulated diguanylate cyclase; [T] COG2199 FOG: GGDEF domain.
 
 0.891
EEE37590.1
Dehydrogenase E1 component family protein; [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 0.852
EEE35453.1
Transcriptional regulator, AraC family; [K] COG2207 AraC-type DNA-binding domain-containing proteins.
  
 0.829
merA_2
Mercuric reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
   
  0.828
merA_1
Mercuric reductase; [S] COG0398 Uncharacterized conserved protein.
       0.823
EEE36937.1
Ggdef family protein; [T] COG2203 FOG: GAF domain.
   
 0.789
Your Current Organism:
Rhodobacteraceae bacterium KLH11
NCBI taxonomy Id: 467661
Other names: R. bacterium KLH11, Rhodobacteraceae bacterium str. KLH11, Rhodobacteraceae bacterium strain KLH11, Rhodobacterales bacterium KLH11
Server load: low (16%) [HD]