STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadCNicotinate-nucleotide diphosphorylase (carboxylating); [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (284 aa)    
Predicted Functional Partners:
EEE35586.1
L-aspartate oxidase; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
 0.999
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 
 0.999
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.950
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 0.938
RKLH11_25
Competence/damage-inducible protein CinA domain protein; [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.
     
 0.873
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.854
sdhA
[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.851
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.848
EEE38056.1
MazG family protein; [R] COG1694 Predicted pyrophosphatase.
    
  0.847
EEE38404.1
Hydrolase, nudix family; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family.
     
 0.847
Your Current Organism:
Rhodobacteraceae bacterium KLH11
NCBI taxonomy Id: 467661
Other names: R. bacterium KLH11, Rhodobacteraceae bacterium str. KLH11, Rhodobacteraceae bacterium strain KLH11, Rhodobacterales bacterium KLH11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.