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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0005Membrane protein, putative. (864 aa)    
Predicted Functional Partners:
SGO_1226
Conserved hypothetical protein; Identified by match to protein family HMM PF08866.
  
     0.720
SGO_0006
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
       0.690
SGO_1019
Glycosyl transferase; Identified by match to protein family HMM PF00535.
 
  
 0.686
SGO_1925
Putative DNA binding protein; Identified by match to protein family HMM PF06279.
  
     0.661
SGO_1149
Pneumococcal vaccine antigen A-like protein.
  
     0.650
SGO_0004
Putative lipoprotein; Identified by match to protein family HMM PF06998.
       0.645
SGO_1867
Conserved hypothetical protein; Identified by match to protein family HMM PF06570.
  
     0.641
SGO_1392
mesH protein; Identified by match to protein family HMM PF04138.
 
  
 0.630
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.596
SGO_1114
Protein of unknown function (DUF1149) superfamily; Identified by match to protein family HMM PF06619.
  
     0.564
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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