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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspBAspartate transaminase; Identified by match to protein family HMM PF00155. (395 aa)    
Predicted Functional Partners:
SGO_0159
Hippurate hydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
  
 
  0.902
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.827
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
    0.812
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
     
 0.801
SGO_1701
Aspartate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
 
 0.682
SGO_0035
Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF01965; match to protein family HMM PF02769; match to protein family HMM TIGR01857.
  
  
 0.660
pheA
Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842.
 
  
 0.624
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.607
SGO_1759
6-phospho-beta-glucosidase; Identified by match to protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family.
   
  
 0.579
SGO_1758
Putative transcriptional regulator; Identified by match to protein family HMM PF01381.
      
 0.576
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.