STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0050Conserved hypothetical protein. (337 aa)    
Predicted Functional Partners:
SGO_0051
Conserved hypothetical protein.
 
  
 0.919
SGO_0052
Transcriptional regulator, PadR family; Identified by match to protein family HMM PF03551.
 
  
 0.863
SGO_0601
Conserved hypothetical protein.
  
  
 0.830
SGO_0094
Lipoprotein, putative.
   
   0.560
SGO_1825
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
   
   0.556
SGO_1738
Conserved hypothetical protein.
  
  
 0.502
SGO_0053
Conserved hypothetical protein.
       0.487
SGO_0734
PspC domain protein; Identified by match to protein family HMM PF04024.
  
  
 0.438
SGO_1461
Putative stress-responsive transcriptional regulator PspC; Identified by match to protein family HMM PF04024.
  
  
 0.438
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
       0.431
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.