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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0088Transcription regulator, AcrR family; Identified by match to protein family HMM PF00440. (173 aa)    
Predicted Functional Partners:
SGO_0090
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
  
     0.743
SGO_0726
Putative transcriptional regulator TetR/AcrR family; Identified by match to protein family HMM PF00440.
  
     0.717
SGO_0087
Transporter, major facilitator family; Identified by match to protein family HMM PF07690.
 
     0.679
SGO_0980
Transcriptional regulator, TetR family domain protein; Identified by match to protein family HMM PF00440.
  
     0.573
SGO_0089
Cation efflux system protein; Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297.
       0.534
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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