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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acdHAlcohol-acetaldehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (883 aa)    
Predicted Functional Partners:
adhA
Alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.
  
 0.983
pfl
Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255.
 
 
 0.968
pta
Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.
   
 
 0.955
sucB
Dihydrolipoamide S-acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF02817.
   
 
 0.944
SGO_1788
Pyruvate formate-lyase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774.
  
 
 0.927
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.914
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.908
SGO_1774
Alcohol dehydrogenase, zinc-containing; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.
     
 0.907
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.906
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
     
 0.902
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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