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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sspBIdentified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167. (1499 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.815
dnaK
DnaK chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.743
SGO_1839
Conserved hypothetical protein.
   
 0.719
SGO_1594
Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.
   
 
 0.709
SGO_0828
Conserved hypothetical protein.
  
     0.700
hsa
Streptococcal hemagglutinin; Identified by similarity to GB:BAA97453.1; match to protein family HMM PF00746; match to protein family HMM TIGR01167.
  
   
 0.698
SGO_0707
LPXTG cell wall surface protein; Identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167.
  
 
 0.696
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.661
SGO_2005
LPXTG cell wall surface protein; Identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167.
 
  
 0.660
cshB
Surface-associated protein CshB; Identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168.
  
 
 0.649
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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