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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0221Glycoprotein endopeptidase; Identified by match to protein family HMM PF00814. (230 aa)    
Predicted Functional Partners:
tsaD
Glycoproteinase family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.998
SGO_0222
Ribosomal-protein-alanine N-acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575.
 
 
 0.971
SGO_0533
Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.
 
 
 0.971
birA
BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.922
SGO_0224
Transport protein-like protein; Identified by match to protein family HMM PF03591.
 
     0.814
SGO_0225
Integral membrane protein; Identified by match to protein family HMM PF05437.
       0.790
celB
DNA internalization-related competence protein celB; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.
 
     0.537
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.536
SGO_0837
uracil-DNA glycosylase; Identified by match to protein family HMM PF03167.
  
    0.525
SGO_0226
Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.
  
    0.522
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.