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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepXX-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family. (759 aa)    
Predicted Functional Partners:
SGO_1799
Identified by match to protein family HMM PF01431; match to protein family HMM PF05649.
      
 0.725
pepC
Identified by match to protein family HMM PF03051; Belongs to the peptidase C1 family.
  
   
 0.711
SGO_1069
Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433.
 
   
 0.638
argS
arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.
      
 0.630
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
      
 0.628
SGO_0235
Glycerol uptake facilitator protein-like protein; Identified by match to protein family HMM PF00230; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.611
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
      
 0.596
SGO_0695
Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
      
 0.587
SGO_0699
Serine/threonine protein phosphatase; Identified by match to protein family HMM PF00149.
      
 0.579
SGO_0238
Beta-lactamase-like or putative esterase; Identified by match to protein family HMM PF00144.
 
   
 0.571
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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