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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0298Two-component response regulator, putative; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (226 aa)    
Predicted Functional Partners:
SGO_0299
Putative histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.973
SGO_1073
Sensor protein CiaH; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.856
SGO_1180
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.854
SGO_1907
Sensor protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.851
SGO_0780
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 0.832
SGO_1416
Putative histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.816
SGO_1504
Histidine kinase; Identified by match to protein family HMM PF02518.
 
 
 0.765
SGO_1175
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
  
   
 0.674
SGO_0484
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.633
SGO_1760
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
  
   
 0.567
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.