node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGO_0747 | SGO_0900 | SGO_0747 | SGO_0900 | Putative methionine synthase. | Conserved domain protein; Identified by match to protein family HMM PF01590. | 0.900 |
SGO_0747 | SGO_1635 | SGO_0747 | SGO_1635 | Putative methionine synthase. | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | 0.901 |
SGO_0747 | SGO_1636 | SGO_0747 | SGO_1636 | Putative methionine synthase. | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | 0.952 |
SGO_0747 | cysD | SGO_0747 | SGO_1334 | Putative methionine synthase. | O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. | 0.919 |
SGO_0747 | cysK | SGO_0747 | SGO_0606 | Putative methionine synthase. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.825 |
SGO_0747 | luxS | SGO_0747 | SGO_0592 | Putative methionine synthase. | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.940 |
SGO_0747 | metE | SGO_0747 | SGO_0310 | Putative methionine synthase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.932 |
SGO_0747 | metF | SGO_0747 | SGO_0311 | Putative methionine synthase. | 5,10-methylenetetrahydrofolate reductase; Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. | 0.720 |
SGO_0747 | metG | SGO_0747 | SGO_1530 | Putative methionine synthase. | methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.908 |
SGO_0747 | metK | SGO_0747 | SGO_0987 | Putative methionine synthase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.957 |
SGO_0900 | SGO_0747 | SGO_0900 | SGO_0747 | Conserved domain protein; Identified by match to protein family HMM PF01590. | Putative methionine synthase. | 0.900 |
SGO_0900 | metE | SGO_0900 | SGO_0310 | Conserved domain protein; Identified by match to protein family HMM PF01590. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
SGO_0900 | metK | SGO_0900 | SGO_0987 | Conserved domain protein; Identified by match to protein family HMM PF01590. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
SGO_1635 | SGO_0747 | SGO_1635 | SGO_0747 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Putative methionine synthase. | 0.901 |
SGO_1635 | SGO_1636 | SGO_1635 | SGO_1636 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | 0.991 |
SGO_1635 | cysD | SGO_1635 | SGO_1334 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. | 0.928 |
SGO_1635 | cysK | SGO_1635 | SGO_0606 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.926 |
SGO_1635 | luxS | SGO_1635 | SGO_0592 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.900 |
SGO_1635 | metE | SGO_1635 | SGO_0310 | L-cysteine desulfhydrase; Identified by match to protein family HMM PF00155. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.901 |
SGO_1636 | SGO_0747 | SGO_1636 | SGO_0747 | Cystathionine gamma-synthase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01053. | Putative methionine synthase. | 0.952 |