STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trx-2Thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family. (104 aa)    
Predicted Functional Partners:
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
 
 0.837
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.
  
  
 0.775
msrA-2
Peptide methionine sulfoxide reductase-like protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.772
SGO_0336
Conserved hypothetical protein.
  
    0.753
SGO_1284
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992.
 
 
 0.740
SGO_1130
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
 
 0.735
SGO_1171
Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
  
 
 0.686
ccdA2
Cytochrome c-type biogenesis protein; Identified by match to protein family HMM PF02683.
  
  
 0.668
SGO_0110
Phosphotyrosine protein phosphatase; Identified by match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.662
SGO_1177
Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
  
 
 0.643
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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