Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pepF-2Oligoendopeptidase; Identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181. (598 aa)    
Predicted Functional Partners:
SGO_1864
X-Pro aminopeptidase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Belongs to the peptidase M24B family.
      
 0.660
pepq
Proline dipeptidase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Belongs to the peptidase M24B family.
      
 0.560
pepV
Dipeptidase PepV; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01886; match to protein family HMM TIGR01887.
  
  
 0.545
csn1
CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...]
      
 0.538
SGO_0348
Reductase.
      
 0.535
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.511
SGO_0343
Transporter, major facilitator family; Identified by match to protein family HMM PF07690.
       0.510
SGO_0341
Lipoprotein, putative.
       0.465
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
  
 0.457
SGO_0758
Glutathione peroxidase; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
       0.455
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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