merA protein (Streptococcus gordonii) - STRING interaction network

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merA

mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (631 aa)

Predicted Functional Partners:

sucB

0.866

SGO_1130

0.835

SGO_1132

0.826

SGO_1900

0.655

acoA

0.574

lplA

0.530

guaB

0.513

msrA

0.470

msrA-2

0.470

fusA

0.458

Your Current Organism:

Streptococcus gordonii

NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGO_1130	SGO_1132	SGO_1130	SGO_1132	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	0.999
SGO_1130	SGO_1900	SGO_1130	SGO_1900	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Identified by match to protein family HMM PF00085.	0.756
SGO_1130	acoA	SGO_1130	SGO_1133	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Acetoin dehydrogenase; Identified by match to protein family HMM PF00676.	0.999
SGO_1130	fusA	SGO_1130	SGO_0206	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	0.618
SGO_1130	guaB	SGO_1130	SGO_0008	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.720
SGO_1130	lplA	SGO_1130	SGO_1129	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545.	0.997
SGO_1130	merA	SGO_1130	SGO_0368	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.835
SGO_1130	msrA	SGO_1130	SGO_0278	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.	0.766
SGO_1130	msrA-2	SGO_1130	SGO_1176	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Peptide methionine sulfoxide reductase-like protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.766
SGO_1130	sucB	SGO_1130	SGO_1131	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	Dihydrolipoamide S-acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF02817.	0.999
SGO_1132	SGO_1130	SGO_1132	SGO_1130	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	0.999
SGO_1132	acoA	SGO_1132	SGO_1133	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	Acetoin dehydrogenase; Identified by match to protein family HMM PF00676.	0.999
SGO_1132	lplA	SGO_1132	SGO_1129	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545.	0.933
SGO_1132	merA	SGO_1132	SGO_0368	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.826
SGO_1132	sucB	SGO_1132	SGO_1131	Acetoin dehydrogenase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.	Dihydrolipoamide S-acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF02817.	0.999
SGO_1900	SGO_1130	SGO_1900	SGO_1130	Identified by match to protein family HMM PF00085.	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	0.756
SGO_1900	merA	SGO_1900	SGO_0368	Identified by match to protein family HMM PF00085.	mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.655
SGO_1900	msrA	SGO_1900	SGO_0278	Identified by match to protein family HMM PF00085.	Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). Involved in protection against oxidative stress when the bacterium enters the host bloodstream and required for maximal growth under aerobic and anaerobic conditions.	0.996
SGO_1900	msrA-2	SGO_1900	SGO_1176	Identified by match to protein family HMM PF00085.	Peptide methionine sulfoxide reductase-like protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.996
acoA	SGO_1130	SGO_1133	SGO_1130	Acetoin dehydrogenase; Identified by match to protein family HMM PF00676.	Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	0.999

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