| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SGO_0386 | SGO_0387 | SGO_0386 | SGO_0387 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | Conserved hypothetical protein; Identified by match to protein family HMM PF01113. | 0.799 |
| SGO_0386 | SGO_1934 | SGO_0386 | SGO_1934 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525. | 0.565 |
| SGO_0386 | birA | SGO_0386 | SGO_0903 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.420 |
| SGO_0386 | dnaJ | SGO_0386 | SGO_0404 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | DnaJ chaparone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.707 |
| SGO_0386 | glnA | SGO_0386 | SGO_0215 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; Belongs to the glutamine synthetase family. | 0.597 |
| SGO_0386 | rpoA | SGO_0386 | SGO_1959 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.569 |
| SGO_0386 | rpoB | SGO_0386 | SGO_1927 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.587 |
| SGO_0386 | rpoC | SGO_0386 | SGO_1926 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.555 |
| SGO_0386 | rpoD | SGO_0386 | SGO_1273 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.656 |
| SGO_0386 | rpoZ | SGO_0386 | SGO_0595 | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.556 |
| SGO_0387 | SGO_0386 | SGO_0387 | SGO_0386 | Conserved hypothetical protein; Identified by match to protein family HMM PF01113. | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | 0.799 |
| SGO_1934 | SGO_0386 | SGO_1934 | SGO_0386 | Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525. | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | 0.565 |
| birA | SGO_0386 | SGO_0903 | SGO_0386 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | 0.420 |
| birA | dnaJ | SGO_0903 | SGO_0404 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | DnaJ chaparone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.461 |
| birA | glnA | SGO_0903 | SGO_0215 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; Belongs to the glutamine synthetase family. | 0.589 |
| birA | rpoA | SGO_0903 | SGO_1959 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.688 |
| birA | rpoD | SGO_0903 | SGO_1273 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.411 |
| dnaJ | SGO_0386 | SGO_0404 | SGO_0386 | DnaJ chaparone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Multidrug-efflux transporter 2 regulator; Identified by match to protein family HMM PF00376. | 0.707 |
| dnaJ | birA | SGO_0404 | SGO_0903 | DnaJ chaparone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.461 |
| dnaJ | rpoC | SGO_0404 | SGO_1926 | DnaJ chaparone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.707 |