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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0395Transcriptional regulator, Cro/CI family; Identified by match to protein family HMM PF01381. (71 aa)    
Predicted Functional Partners:
SGO_0394
Membrane protein, putative.
       0.797
SGO_0396
Transcriptional regulator, PadR family; Identified by match to protein family HMM PF01047; match to protein family HMM PF03551.
  
    0.534
SGO_0397
Conserved hypothetical protein.
       0.522
SGO_0393
D-alanyl-D-alanine carboxypeptidase; Identified by match to protein family HMM PF02557.
       0.504
SGO_0399
Membrane protein, putative.
       0.477
SGO_0398
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005.
       0.476
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.