Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SGO_0430LPXTG cell wall surface protein; Identified by match to protein family HMM TIGR01167. (886 aa)    
Predicted Functional Partners:
SGO_0707
LPXTG cell wall surface protein; Identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167.
  
 
 0.708
SGO_0796
Conserved hypothetical protein; Identified by match to protein family HMM PF00413.
  
     0.699
gtfB
Conserved hypothetical protein; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
  
   0.697
nss
Nucleotide sugar synthetase-like protein.
  
   0.675
SGO_0890
LPXTG cell wall surface protein, collagen binding domain; Identified by match to protein family HMM PF00746; match to protein family HMM PF05737; match to protein family HMM TIGR01167.
      
 0.638
sspB
Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167.
 
 
 0.634
sspA
Identified by match to protein family HMM PF00746; match to protein family HMM PF06696; match to protein family HMM PF08363; match to protein family HMM TIGR01167.
 
 
 0.622
gtaA
Glycosyl transferase, group 1 SP1758; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
  
   0.620
scpA
Uncharacterised ACR, COG1354; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.608
SGO_0484
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
   0.590
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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