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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO_0449Identified by match to protein family HMM PF00857. (167 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.816
SGO_0448
Conserved hypothetical protein TIGR00488; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488.
     
 0.802
rsfS
Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.790
SGO_0446
Conserved hypothetical protein TIGR00253; Identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253.
       0.717
SGO_0451
Methyltransferase; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.
   
   0.632
tmcAL
Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
     
 0.613
birA
BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.532
SGO_0444
HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; Identified by match to protein family HMM TIGR01549; match to protein family HMM TIGR01662; match to protein family HMM TIGR01668.
       0.525
SGO_0445
Identified by match to protein family HMM PF01926.
       0.525
Mga
Mga-like regulatory protein; Identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280.
   
    0.461
Your Current Organism:
Streptococcus gordonii
NCBI taxonomy Id: 467705
Other names: S. gordonii str. Challis substr. CH1, Streptococcus gordonii ATCC 35105, Streptococcus gordonii str. Challis substr. CH1, Streptococcus gordonii str. Challis substr. DL1, Streptococcus gordonii str. Challis substr. V288
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